Preheat oven to 350 degrees.
Heat medium-large skillet to low-medium heat.
Combine the ingredients for the burger in a medium bowl. Mix thoroughly. Let sit for about 5 minutes.
Combine the ingredients for the topping in a small bowl and set aside to top later.
In a small skillet, combine and cook over medium heat the squash spirals.
Form shrimp mixture into roughly bun size patties, it should yield about 6 patties.
Butter, oil, or spray the heated skillet.
Place each patty a few inches apart and cook for about 4-6 minutes each side.
Check the squash and stir. If all/most liquid is out, turn off heat.
Remove each patty and put on an oven safe pan.
Cook the patties for 12-15 minutes in the oven. If browning too fast, cover with aluminum foil.
If desired, put cheese on burgers for the last few minutes of baking.
Place a portion of the squash spirals on the bottom of a bun.
Spread the spicy mayo over the top of the bun.
Place patties on buns and enjoy.